A breakthrough diet pill that attacks cravings and appetite.
While most diet pills are a dime a dozen, once in awhile a promising weight loss pill hits the market that causes even the most skeptical of medical professionals to stop and listen. Contrave is one such product.
Developed by Orexigen Therapeutics, Contrave is actually the combination of two different drugs: The antidepressant medication, buproprion, or Wellbutrin, and the drug naltrexone, which is used to treat alcohol and opiate addiction.
Rather than working to block fat or starches like many prescribed diet pills do, Contrave unleashes its power on the brain, where it works to quell cravings in the brain's highly complex behavior-reward center, and also to temper appetite.
In late-stage clinical trials, Contrave has fared much better than the FDA's standards for improving weight loss, exceeding by five percent. Rather, those who took Contrave while also following a diet and exercise program lost between nine and 15 percent of their body weight while those who did not lost just about five percent of their body weight.
Contrave has also shown few side effects and notably absent are mental health and uncomfortable physical side effects that often come from taking weight loss pills. In fact, those studied showed an improved quality of life while taking the pill.
Contrave is being slated as a chronic diet pill; if you take it and lose weight you will have to continue to take it in order to maintain lost weight. One of the downfalls with most of the diet pills on the market, whether or not they require a prescription, is that once you stop taking them, weight is easily regained. Since Contrave specifically acts on the centers of the brain that govern overeating behaviors and craving desires, there is hope that its ability to suppress these processes will lead to long-term weight loss.
As of July 2009, Orexigen Therapeutics is seeking FDA approval. When and if Contrave is approved for consumer use, it will require a prescription from a medical professional.
- Shows promise in late-stage clinical trials
- Exceeding FDA standards in trials
- Cocktail-like therapy may be the benchmark for future diet pills
- Few side effects
- Weight loss is greater than placebo alone
- If approved, requires a prescription
- May need to take diet pill chronically
- Weight loss advantage is not that significant
- Not a magic solution to healthy eating behaviors and to a healthy weight
- Still awaiting FDA approval
Contrave is a breakthrough weight loss drug because it contains both buproprion and naltrexone.
Buprupion is also known as the branded prescription drug Wellbutrin, a quality anti-depressant.
Naltrexone is a prescription drug used to treat addiction, in cases such as smoking, alcohol or even opiates.ADMINISTRATION
Contrave will likely be taken daily. Since the drug is awaiting FDA approval, precise dosage instructions are not yet available.DIET and EXERCISE
A low-fat and low-calorie diet and regular exercise program is followed while taking Contrave. Since this drug does not act on the stomach, there are currently no specific foods that need to be avoided or a particular style of eating that needs to be followed while taking it.CONCLUSION
Contrave is a new weight loss pill that shows promise for being able to act on the brain's pathways that control cravings and appetite. This new kind of drug, which combines two different kinds of psychopharmaceuticals, is predicted to be the wave of the future for diet pills.
Contrave is still awaiting FDA approval.Common Misspellings
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