The Food and Drug Administration (FDA) is advising consumers not to purchase or use “Japan Rapid Weight Loss Diet Pills Green.” This product is used for weight loss and sold on various websites, such as Amazon.com and distributed by Xiushentang.
According to the FDA website, a laboratory analysis confirmed that “Japan Rapid Weight Loss Diet Pills Green” contains undeclared phenolphthalein.
According to the Britannica, Phenolphthalein is a potent laxative, which acts within 6–8 hours; its effects may last 3–4 days. Such adverse reactions as kidney irritation or skin rash may occur. As an indicator of the pH of a solution, it is colorless below pH 8.0 and attains a deep red hue above pH10.0.
It was discovered in 1871 by the German chemist Adolf von Baeyer, who prepared it by fusing phenol and ophthalmic anhydride in the presence of sulfuric acid or zinc chloride. This is a solution used in chemical experiments and is also suspect of causing cancer. (more…)
Qnexa, a diet pill created by Vivus, Inc., that claims to help dieters lose 10% of their weight when combined with diet and exercise, has been approved by the FDA advisory panel in a landslide vote of 20-2.
The panel had previously rejected the the pill due to safety concerns, which has left its opponents concerned. Since the FDA typically follows the advice of its advisory panel, the drug is likely to be approved by mid-April.
Previous concerns about the drug are still present. And if the pill does go on shelves, potential users should be aware of that. One of Qnexa’s main ingredients is phentermine, a type of amphetamine that stimulates the nervous system and increases heart rate and blood pressure. It’s commonly used in diet pills since it suppresses appetite, and was woefully recognized as the “Phen” in the weight loss drug Fen-Phen, which was yanked from the market by the FDA in 1997 after being deemed too dangerous for consumption. (more…)
Dr. Oz will speak with women from across the nation as they explain their obsession with a new pill popping fad. These women will admit to feeling energy boosts, increased concentration, and some women will discuss how the pills have helped them lose weight.
Dr. Oz will interview one pill-using mother who said, “I feel focused, have more energy, and feel like super mom.” Another mother shares how she’s already lost 35 pounds while using the pills and yet another mom simply states, “I really can’t imagine my life without being on this.”
GNC recently signed a contract to exclusively market a new diet supplement called pAGG in its 1900 stores. PAGG is an acronym for its ingredients policosanol, alpha-lipoic acid, decaffeinated green tea, aged garlic extract and biotin. So is this the next weight loss miracle supplement? This supplement was recently discussed in the New York Times Bestseller The 4-Hour Body and its supplier NewHealth Solutions says to look no further for a fast and effective way to lose weight. I say let’s take a closer look.
It’s hard to know where to begin on this one. I see a lot of red flags. Policosanol is a mixture of fatty alcohol most commonly made from sugar cane wax. This product has been extensively studied in Cuba and is used there as a cure for almost anything. Policosanol is indicated for maintaining healthy cholesterol levels. Not only have many trials shown that policosanol does not significantly decrease cholesterol levels but that it also could increase the risk of bleeding, specifically from the gums or nose. Fish oils may be a better alternative to achieve healthy cholesterol levels.
If, at first, you don’t succeed try, try again. That’s what Vivus, the makers of a diet drug called Qnexa did by resubmitting their drug approval application to the FDA advisory committee and it is now one step closer to being approved. The initial application was rejected because of two main concerns: risk of cardiac events like heart attacks and risk to women of child bearing age and women who may be pregnant.
Qnexa is a combination drug of phentermine and topiramate. Both these drugs are currently available by prescription which makes the approval process a little bit easier for Qnexa because there already are a lot of clinical trials and data available about these drugs. Phetermine increases metabolism while topiramate is used for seizures, migraine prevention and as an adjunct therapy for conditions like bipolar disorder. Weight loss for topiramate is really more of a glorified side effect that is believed to be caused by an increase in energy for the patient and increased feeling of fullness after eating because the digestive tract is slowed down.
Qnexa is a capsule made up of immediate release phentermine and extended release topiramate which would have a longer duration of action and is taken once daily. Vivus is currently studying the use of a low, moderate and high dose combination. Qnexa is indicated for people who have a BMI of 30 or higher or overweight patients with a BMI greater than 27 who have other conditions like hypertension, type 2 diabetes, high cholesterol, and fat that is most prominent on the abdomen also known as belly fat. The most common side effects of this combination drug include a prickling or tingling sensation, dry mouth, constipation, and headache.