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25 Years of Weight Loss with Oprah

Weight Loss Show Stoppers on Oprah

One of Oprah's messages is that you should live the best life possible, and for many Americans, this means getting down to a healthy weight. During the 24 seasons that her show has been on air, Oprah addressed all kinds of weight-loss and body-image issues, even her own. From ordinary but extraordinary Americans to celebrities like Kirstie Alley and to Oprah herself, here is a slide show of 12 of the most memorable weight loss stories profiled on Oprah over the years.

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