This summer, Biggest Loser 6 contestants Phillip and Amy Parham published their first book, “The 90-Day Fitness Challenge,” and continued their journey of helping Americans get fit. For August and September, they are the featured sponsors of the DietsInReview.com newsletter, and below you can learn more about their mission.

When “Jamie Oliver’s Food Revolution” launched on ABC, the UK native set out to change the way people eat in what has been dubbed “the fattest city in America,” Huntington, West Virginia. But when he appeared on the “Late Show with David Letterman,” Letterman told him his mission was hopeless. The White House recently declared war on childhood obesity. There’s no doubt we have a battle on our hands—but is it already lost?

“Not even close!” say Phil Parham and Amy Parham, stars from NBC’s “The Biggest Loser.” Combined, Phil and Amy lost more than 250 pounds on the hit TV show. Viewers related to the Parhams immediately, as their struggle with weight was—like it is for most people—more than just about food.
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Overeating is a complex set of circumstances that range from psychological to simple ignorance about the foods we eat. But, what if when it’s all said and done, doctors could simply turn off your hunger like a light switch?

The answer could lie in a molecule known as MIC-1.

Australian scientists have figured out how to switch hunger on and off using MIC-1. The discovery could stop weight loss in terminally ill patients or produce weight loss in the morbidly obese. MIC-1 is produced by cancers and targets receptors in the brain that switch off appetite.

Sam Breit at St Vincent’s Centre for Immunology, who originally cloned the MIC-1 gene, believes the findings could have a significant impact on a range of appetite-related disorders.